- Apple - Adam Katz
- Balloon - Ben Cross
- Nate Groth (Was fired during Season 1, causing a frequent re-use of lines. Rehired for Season 2 until Let 'Er R.I.P.)
- Baseball - Adam Katz
- Bomb - Max Weissmann
- Bow - Taylor Grodin
- Box - Derek Napolitano (In Breaking The Ice only, as secret message)
- Cherries - Derek Napolitano
- Cheesy - Aaron Shapiro
- Dough - Taylor Grodin
- Fan- Brian Koch
- Knife - Justin Chapman
- Lightbulb - Michael Bruzzone
- Marshmallow - Dee Cashin
- AmandaRulez85 (Voice actor until War De Guacamole)
- Adam Katz (Main voice actor for the rest of Season 1)
- Microphone - Hailey Chapman
- Nickel - Adam Katz
- OJ - Taylor Grodin
- Paintbrush - Taylor Grodin
- TotalDramaFantasy (until A Lemony Lesson)
- Paper - Justin Chapman
- Pepper - Alexa Chapman
- Pickle - Derek Napolitano
- Salt - Alexa Chapman
- Soap - Kacie Chapman (singing voice provided by Vibha Melkote)
- Suitcase - Samuel Thornbury
- Tissues - Taylor Grodin
- Taco - Aceland Alexander Kent
- Adam Katz (Main voice actor in Season 1 only)
- Adam Katz's sister (unknown)
- Test Tube - Adam Katz
- Trophy - Justin Napolitano
- Yin-Yang - Marco Bonomo
- MePhone4 - Mark Katz
- Christian Potenza (S1 E1, S1 E18 (briefly))
- Toilet - Taylor Grodin
- MePad - Conrad Collins
- MePhone4S - Brian Koch
- Adam - Adam Katz
- Nick-Le - Nate Groth
- Santa Claus - Brian Koch
- Tyler Bungard - Justin Miller
- Life Ring - Adam Katz
- Pizza Cutter - Derek Napolitano
- MePhone5 - Damario Watson
- MePhone5S - Issac Suh
- MePhone5C - Jill Katz
- Judge Gavel - Stephen Boyer
- Rusty Jo - Adam Dormi
T-Shirt Contest Recommended Characters
Bold = This is the character's current voice actor.
Italics = This voice actor has been replaced or fired.
- Of all the characters, Adam Katz has voiced the most at 10.
- Taylor Grodin voices the second most characters at 6. Although he originally only voiced one.
- The original voice actors for Balloon, Marshmallow, Paintbrush, Pepper, and Salt have all been replaced.
- Nate Groth was fired in the first season, therefore his lines were re-used to give Balloon his voice. He returned in Season 2, but was replaced again by Ben Cross.
- Brian Koch did the recap at the beginning of nearly every Season 1 episode.
- OJ, MePhone4, Pickle and Adam are the only characters who's voice is not distorted or changed to create their final voices, as their voices are the actual voices of the voice actors.
- Of all the characters, Pepper has had the most voice actors, at 5
- Adam and Justin were the only two people to have more than one voice role when the series first started.
- Justin Chapman is the only voice actor who has continued to voice the same two characters throughout the entire series without voicing any new characters.
- On occasion, Adam will voice a character when the voice actor has not sent in the line.
- Derek, Justin, Taylor, Brian and Adam are the only voice actors to show their face.
- It's revealed that Mark Katz, the voice for MePhone4, is Adam Katz's father. And Jill Katz, the voice actor for MePhone5C, is his mother.